How VESIcare works

VESIcare is thought to help control the bladder muscle

It's all about what's going on with your internal plumbing. That's because a normal bladder and an overactive bladder don't always work the same way. Here's what happens:

  • As your bladder fills with urine, it expands like a balloon. Once it expands to its full size, it sends a message to your brain, letting it know you're ready to go to the bathroom. When you go to the bathroom, your bladder muscle contracts, starting the flow of urine.

  • With an overactive bladder, your bladder muscle contracts before your bladder expands to its full size, making it work overtime. This can make you feel those frequent urges and leaks you might be experiencing. In other words, your internal plumbing doesn't always work the way it should.

  • Medications like VESIcare are thought to work by interacting with natural body chemicals that cause the bladder muscle to contract.

    Get a closer look at an overactive bladder by exploring
    the Internal Plumbing Guide.

Dr. Reed says:

“When I diagnose a patient with overactive bladder, I try to explain
that the bladder is actually a muscle, and in overactive bladder, the muscle has a tendency to spasm, or abnormally contract.” Hear more

Receive recipes, exercise tips, money-saving opportunities, resources, and tools to
help you manage your OAB symptoms.

Track your symptoms

A helpful tool to chart your habits,
schedule, and challenges.


VESIcare is for overactive bladder with symptoms of urgency, frequency, and leakage. The recommended dose of VESIcare is 5 mg once daily.
If the 5-mg dose is well tolerated, your doctor may increase the dose to 10 mg once daily.


VESIcare is not for everyone. If you have certain stomach or glaucoma problems, or trouble emptying your bladder, do not take VESIcare. VESIcare may cause allergic reactions that may be serious. If you experience swelling of the face, lips, throat, or tongue, stop taking VESIcare and get emergency help. Tell your doctor right away if you have severe abdominal pain, or become constipated for three or more days. VESIcare may cause blurred vision, so use caution while driving or doing unsafe tasks. Common side effects are dry mouth, constipation, and indigestion.

Please see accompanying complete Prescribing Information.

Overactive bladder (OAB)

Overactive bladder occurs when you cannot control your bladder contractions. When these muscle contractions happen too often or cannot be controlled you can get symptoms of overactive bladder, which include urinary frequency, urinary urgency, and urinary incontinence (leakage).


The balloon-shaped organ inside the body that holds urine.

Bladder tracker

A record of your daily bathroom routine

Bladder training

A method of going to the bathroom on a regular schedule and emptying the bladder completely


The ability to control the timing of urination or a bowel movement

Contraction or Contracts

To shrink, tighten, or become smaller.


The need to go to the bathroom more than eight times in a 24-hour period


The loss of bladder control that results in leakage

Kegel exercises

Exercises to tighten and relax the bladder muscle and hold the bladder in its proper position.

Stress incontinence

Leakage due to weak pelvic muscles that happens while coughing, sneezing, laughing, lifting, jumping, or other physical activity


A sudden sense of needing to go to the bathroom right away

Urinary tract (or urinary system)

The system in the body that removes waste from the blood and carries it out of the body through urine

Urinary tract infection (UTI)

An illness caused by foreign bacteria, viruses, or yeast that grows in the urinary tract


The liquid that contains extra water and waste that passes from the body.


A doctor who specializes in diseases of the male and female urinary system and the male reproductive system


A drug or substance that increases the volume of urine output.

Urge urinary incontinence

The strong, sudden need to urinate due to bladder spasms or contractions.