Risks & side effects

This information does not take the place of talking with your doctor or healthcare professional about
your medical condition or treatment.

  • Who should NOT take VESIcare?

    • Do not take VESIcare if you:

      • are not able to empty your bladder (urinary retention)
      • have delayed or slow emptying of your stomach (gastric retention)
      • have an eye problem called "uncontrolled narrow-angle glaucoma"
      • are allergic to solifenacin succinate or any of the ingredients in VESIcare.

      See the last section of this page for a complete list of ingredients.

  • What should I tell my doctor before taking VESIcare?

    • Before you take VESIcare, tell your doctor if you:

      • Have any stomach or intestinal problems or problems with constipation
      • Have trouble emptying your bladder or have a weak urine stream
      • Have an eye problem called "narrow-angle glaucoma"
      • Have liver problems
      • Have kidney problems
      • Have a rare heart problem called "QT prolongation" or are taking medicines known to cause "QT prolongation"
      • Are pregnant or plan to become pregnant. It is not known if VESIcare will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
      • Are breast feeding or plan to breast feed. It is not known if VESIcare passes into your breast milk. You and your doctor should decide if you will take VESIcare or breast feed. You should not do both.
  • Tell your doctor about all the medicines you take

    • Tell your doctor about all the medicines you take, whether prescription or nonprescription, as well as any vitamins or supplements. VESIcare may affect the way other medicines work, and other medicines may affect how VESIcare works.

  • How should I take VESIcare?

      • Take VESIcare exactly as your doctor tells you to take it.
      • You should take 1 VESIcare tablet 1 time a day.
      • You should take VESIcare with water and swallow the tablet whole.
      • You can take VESIcare with or without food.
      • If you miss a dose of VESIcare, begin taking VESIcare again the next day. Do not take 2 doses of VESIcare the same day.
      • If you take too much VESIcare, call your doctor or go to the nearest hospital emergency room right away.
  • What should I avoid while taking VESIcare?

    • VESIcare can cause blurred vision or drowsiness. Do not drive or operate heavy machinery until you know how VESIcare affects you.

  • What are the possible side effects of VESIcare?

    • VESIcare may cause serious side effects including:

      • Serious allergic reaction.
        Stop taking VESIcare and get medical help right away if you have:
        • –hives, skin rash or swelling
        • –severe itching
        • –swelling of your face, mouth or tongue
        • –trouble breathing

      The most common side effects of VESIcare include:

      • Dry mouth
      • Constipation. Call your doctor if you get severe stomach area (abdominal) pain or become constipated for 3 or more days.
      • Urinary tract infection
      • Blurred vision
      • Heat exhaustion or heat-stroke. This can happen when VESIcare is used in hot environments. Symptoms may include:
        • –decreased sweating
        • –dizziness
        • –tiredness
        • –nausea
        • –increase in body temperature

      Tell your doctor if you have any side effect that bothers you or that does not go away.

      These are not all the possible side effects of VESIcare. For more information, ask your doctor or pharmacist.

      Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

  • How should I store VESIcare?

      • Store VESIcare at 59° to 86°F (15° to 30°C). Keep the bottle closed.
      • Safely throw away medicine that is out of date or that you no longer need.

      Keep VESIcare and all medicines out of the reach of children.

  • General information about VESIcare

    • Medicines are sometimes prescribed for purposes other than those listed in Patient Information leaflets. Do not use VESIcare for a condition for which it was not prescribed. Do not give VESIcare to other people, even if they have the same symptoms you have. It may harm them.

  • What are the ingredients in VESIcare?

    • Active ingredient: solifenacin succinate
      Inactive ingredients: lactose monohydrate, corn starch, hypromellose 2910, magnesium stearate, talc, polyethylene glycol 8000 and titanium dioxide with yellow ferric oxide (5 mg VESIcare tablet) or red ferric oxide (10 mg VESIcare tablet)

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VESIcare is for overactive bladder with symptoms of urgency, frequency, and leakage. The recommended dose of VESIcare is 5 mg once daily.
If the 5 mg dose is well tolerated, your doctor may increase the dose to 10 mg once daily.


VESIcare is not for everyone. If you have certain stomach or glaucoma problems, or trouble emptying your bladder, do not take VESIcare. VESIcare may cause allergic reactions that may be serious. If you experience swelling of the face, lips, throat, or tongue, stop taking VESIcare and get emergency help. Tell your doctor right away if you have severe abdominal pain, or become constipated for three or more days. VESIcare may cause blurred vision, so use caution while driving or doing unsafe tasks. Common side effects are dry mouth, constipation, and indigestion.

Please see accompanying complete Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Overactive bladder (OAB)

Overactive bladder occurs when you cannot control your bladder contractions. When these muscle contractions happen too often or cannot be controlled you can get symptoms of overactive bladder, which include urinary frequency, urinary urgency, and urge urinary incontinence (leakage).


The balloon-shaped organ inside the body that holds urine.

Bladder tracker

A record of your daily bathroom routine

Bladder training

A method of going to the bathroom on a regular schedule and emptying the bladder completely


The ability to control the timing of urination or a bowel movement

Contraction or Contracts

To shrink, tighten, or become smaller.


The need to go to the bathroom more than eight times in a 24-hour period.


The loss of bladder control that results in leakage.

Kegel exercises

Exercises to tighten and relax the bladder muscle and hold the bladder in its proper position.

Stress incontinence

Leakage due to weak pelvic muscles that happens while coughing, sneezing, laughing, lifting, jumping, or other physical activity


A sudden sense of needing to go to the bathroom right away.

Urinary tract (or urinary system)

The system in the body that removes waste from the blood and carries it out of the body through urine

Urinary tract infection (UTI)

An illness caused by foreign bacteria, viruses, or yeast that grows in the urinary tract


The liquid that contains extra water and waste made by the kidneys that passes from the body.


A doctor who specializes in diseases of the male and female urinary system and the male reproductive system


A drug or substance that increases the volume of urine output.

Urge urinary incontinence

The strong, sudden need to urinate due to bladder spasms or contractions.